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129
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BMCBI
2010
161views more  BMCBI 2010»
15 years 3 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
125
Voted
BMCBI
2008
145views more  BMCBI 2008»
15 years 3 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
106views more  BMCBI 2008»
15 years 3 months ago
A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selec
Background: Cell viability is one of the basic properties indicating the physiological state of the cell, thus, it has long been one of the major considerations in biotechnologica...
Ning Wei, Erwin Flaschel, Karl Friehs, Tim W. Natt...
123
Voted
BMCBI
2007
105views more  BMCBI 2007»
15 years 3 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
126
Voted
BMCBI
2008
95views more  BMCBI 2008»
15 years 3 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
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