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143
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BMCBI
2005
97views more  BMCBI 2005»
15 years 3 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
132
Voted
BMCBI
2007
106views more  BMCBI 2007»
15 years 3 months ago
Simultaneous identification of long similar substrings in large sets of sequences
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
Jürgen Kleffe, Friedrich Möller, Burghar...
132
Voted
BMCBI
2005
121views more  BMCBI 2005»
15 years 3 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
136
Voted
BMCBI
2005
125views more  BMCBI 2005»
15 years 3 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
133
Voted
TIT
1998
96views more  TIT 1998»
15 years 3 months ago
Sequential Prediction of Individual Sequences Under General Loss Functions
Abstract— We consider adaptive sequential prediction of arbitrary binary sequences when the performance is evaluated using a general loss function. The goal is to predict on each...
David Haussler, Jyrki Kivinen, Manfred K. Warmuth