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126
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BMCBI
2010
95views more  BMCBI 2010»
15 years 3 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
150
Voted
TKDE
2008
156views more  TKDE 2008»
15 years 3 months ago
A Framework for Mining Sequential Patterns from Spatio-Temporal Event Data Sets
Given a large spatio-temporal database of events, where each event consists of the fields event ID, time, location, and event type, mining spatio-temporal sequential patterns ident...
Yan Huang, Liqin Zhang, Pusheng Zhang
134
Voted
BMCBI
2007
94views more  BMCBI 2007»
15 years 3 months ago
Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context
Background: Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of large...
Jeremiah J. Faith, Andrew J. Olson, Timothy S. Gar...
179
Voted
BMCBI
2005
201views more  BMCBI 2005»
15 years 3 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
167
Voted
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
15 years 1 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen