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» Objects-early tools: a demonstration
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APIN
2006
136views more  APIN 2006»
15 years 2 months ago
Cell modeling with reusable agent-based formalisms
Biologists are building increasingly complex models and simulations of cells and other biological entities, and are looking at alternatives to traditional representations. Making ...
Ken Webb, Tony White
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 2 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2006
119views more  BMCBI 2006»
15 years 2 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2006
141views more  BMCBI 2006»
15 years 2 months ago
Identification of consensus RNA secondary structures using suffix arrays
Background: The identification of a consensus RNA motif often consists in finding a conserved secondary structure with minimum free energy in an ensemble of aligned sequences. How...
Mohammad Anwar, Truong Nguyen, Marcel Turcotte
BMCBI
2006
95views more  BMCBI 2006»
15 years 2 months ago
A quantitative analysis of secondary RNA structure using domination based parameters on trees
Background: It has become increasingly apparent that a comprehensive database of RNA motifs is essential in order to achieve new goals in genomic and proteomic research. Secondary...
Teresa W. Haynes, Debra J. Knisley, Edith Seier, Y...