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BMCBI
2010
14 years 9 months ago
2010
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
14 years 9 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
14 years 9 months ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
105
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BMCBI
2008
14 years 9 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
103
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BMCBI
2008
14 years 9 months ago
2008
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...