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BIOSTEC
2008
148views Healthcare» more  BIOSTEC 2008»
14 years 11 months ago
Representing and Reasoning with Temporal Constraints in Clinical Trials Using Semantic Technologies
Clinical trial protocols include schedule of clinical trial activities such as clinical tests, procedures, and medications. The schedule specifies temporal constraints on the seque...
Ravi D. Shankar, Susana B. Martins, Martin J. O'Co...
ICGA
1997
122views Optimization» more  ICGA 1997»
14 years 11 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
BMCBI
2010
133views more  BMCBI 2010»
14 years 10 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...
BMCBI
2010
120views more  BMCBI 2010»
14 years 10 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang