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» On Complexity Measures for Biological Sequences
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RECOMB
2009
Springer
15 years 10 months ago
Finding Biologically Accurate Clusterings in Hierarchical Tree Decompositions Using the Variation of Information
Abstract. Hierarchical clustering is a popular method for grouping together similar elements based on a distance measure between them. In many cases, annotation information for som...
Saket Navlakha, James Robert White, Niranjan Nagar...
CPM
2005
Springer
97views Combinatorics» more  CPM 2005»
15 years 3 months ago
On the Complexity of Sparse Exon Assembly
Gene structure prediction is one of the most important problems in computational molecular biology. It involves two steps: the first is finding the evidence (e.g. predicting spl...
Carmel Kent, Gad M. Landau, Michal Ziv-Ukelson
BMCBI
2010
90views more  BMCBI 2010»
14 years 9 months ago
Local alignment of generalized k-base encoded DNA sequence
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
Nils Homer, Stanley F. Nelson, Barry Merriman
BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
RECOMB
2009
Springer
15 years 10 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...