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» On Complexity Measures for Biological Sequences
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SPIRE
2005
Springer
15 years 4 months ago
Normalized Similarity of RNA Sequences
We introduce a normalized version of the LCS metric as a new local similarity measure for comparing two RNAs. An O(n2 m lg m) time algorithm is presented for computing the maximum ...
Rolf Backofen, Danny Hermelin, Gad M. Landau, Oren...
BMCBI
2008
142views more  BMCBI 2008»
14 years 11 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2007
109views more  BMCBI 2007»
14 years 11 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
RECOMB
2008
Springer
15 years 11 months ago
CompostBin: A DNA Composition-Based Algorithm for Binning Environmental Shotgun Reads
A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional method...
Sourav Chatterji, Ichitaro Yamazaki, Zhaojun Bai, ...
BMCBI
2008
152views more  BMCBI 2008»
14 years 11 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...