Given the heterogeneous nature of biological data and their intensive use in many tools, in this paper we propose a semantic data access and integration (DAI) service, based on th...
Giovanni Aloisio, Massimo Cafaro, Italo Epicoco, S...
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...