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» On Complexity Measures for Biological Sequences
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BMCBI
2005
133views more  BMCBI 2005»
14 years 11 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
MST
2006
149views more  MST 2006»
14 years 11 months ago
Parameterized Intractability of Distinguishing Substring Selection
A central question in computational biology is the design of genetic markers to distinguish between two given sets of (DNA) sequences. This question is formalized as the NP-comple...
Jens Gramm, Jiong Guo, Rolf Niedermeier
BMCBI
2004
167views more  BMCBI 2004»
14 years 11 months ago
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Background: The identification of relevant biological features in large and complex datasets is an important step towards gaining insight in the processes underlying the data. Oth...
Yvan Saeys, Sven Degroeve, Dirk Aeyels, Pierre Rou...
GCB
2009
Springer
180views Biometrics» more  GCB 2009»
15 years 5 months ago
2D Projections of RNA Folding Landscapes
Abstract: The analysis of RNA folding landscapes yields insights into the kinetic folding behavior not available from classical structure prediction methods. This is especially imp...
Ronny Lorenz, Christoph Flamm, Ivo L. Hofacker
CIARP
2005
Springer
15 years 4 months ago
Development and Validation of an Algorithm for Cardiomyocyte Beating Frequency Determination
The Chagas disease or Tripanosomiasis Americana affects between 16 and 18 million people in endemic areas. This disease affects the beating rate of infected patients’ cardiomyocy...
Demian Wassermann, Marta Mejail