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» On Compressibility of Protein Sequences
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BMCBI
2010
136views more  BMCBI 2010»
15 years 19 days ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
NAR
2008
152views more  NAR 2008»
15 years 14 days ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
85
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SAC
2005
ACM
15 years 6 months ago
Comparing approaches to predict transmembrane domains in protein sequences
There are today several systems for predicting transmembrane domains in membrane protein sequences. As they are based on different classifiers as well as different pre- and post-p...
Paul Davidsson, Johan Hagelbäck, Kenny Svenss...
70
Voted
BMCBI
2008
88views more  BMCBI 2008»
15 years 19 days ago
Use of machine learning algorithms to classify binary protein sequences as highly-designable or poorly-designable
Background: By using a standard Support Vector Machine (SVM) with a Sequential Minimal Optimization (SMO) method of training, Na
Myron Peto, Andrzej Kloczkowski, Vasant Honavar, R...
104
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 19 days ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...