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» On Compressibility of Protein Sequences
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97
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BMCBI
2006
85views more  BMCBI 2006»
15 years 19 days ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
133
Voted
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
14 years 10 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
111
Voted
CIBCB
2007
IEEE
15 years 7 months ago
A Comparison of Sequence Kernels for Localization Prediction of Transmembrane Proteins
Abstract— We applied Support Vector Machines to the prediction of the subcellular localization of transmembrane proteins, and compared the performance of different sequence kerne...
Stefan Maetschke, Marcus Gallagher, Mikael Bod&eac...
INFOSCALE
2006
ACM
15 years 6 months ago
Scalable hardware accelerator for comparing DNA and protein sequences
Abstract— Comparing genetic sequences is a well-known problem in bioinformatics. Newly determined sequences are being compared to known sequences stored in databases in order to ...
Philippe Faes, Bram Minnaert, Mark Christiaens, Er...
77
Voted
BMCBI
2004
77views more  BMCBI 2004»
15 years 13 days ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich