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100
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
BMCBI
2006
14 years 10 months ago
2006
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
88
Voted
CAGD
2006
14 years 10 months ago
2006
Given a smooth surface, a blue (red) ridge is a curve such that at each of its points, the maximum (minimum) principal curvature has an extremum along its curvature line. Ridges a...
BMCBI
2007
14 years 10 months ago
2007
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
94
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...