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95
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BMCBI
2010
182views more  BMCBI 2010»
15 years 24 days ago
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...
Jo A. Helmuth, Grégory Paul, Ivo F. Sbalzar...
BMCBI
2008
113views more  BMCBI 2008»
15 years 24 days ago
Investigating selection on viruses: a statistical alignment approach
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
83
Voted
BMCBI
2010
98views more  BMCBI 2010»
15 years 24 days ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
78
Voted
BMCBI
2008
106views more  BMCBI 2008»
15 years 24 days ago
Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spect
Background: Mass spectrometry for biological data analysis is an active field of research, providing an efficient way of high-throughput proteome screening. A popular variant of m...
Wouter Meuleman, Judith Y. M. N. Engwegen, Marie-C...
BMCBI
2010
224views more  BMCBI 2010»
15 years 24 days ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
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