To cope with the large amount of biological sequences being produced, a significant number of genes and proteins have been annotated by automated tools. A protein annotation is an...
Abstract. We explore a new general-purpose heuristic for nding highquality solutions to hard optimization problems. The method, called extremal optimization, is inspired by self-or...
Stefan Boettcher, Allon G. Percus, Michelangelo Gr...
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
A unified evolutionary approach to coplanar radiotherapy inverse planning is proposed. It consists of a genetic algorithm-based framework that solves with little modification tr...
Vitoantonio Bevilacqua, Giuseppe Mastronardi, Gius...