We present a general boosting method extending functional gradient boosting to optimize complex loss functions that are encountered in many machine learning problems. Our approach...
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Abstract. Side-chain prediction is an important subproblem of the general protein folding problem. Despite much progress in side-chain prediction, performance is far from satisfact...
A new class of data structures called "bumptrees" is described. These structures are useful for efficiently implementing a number of neural network related operations. A...