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» On Pairing Inversion Problems
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BMCBI
2008
163views more  BMCBI 2008»
15 years 26 days ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
122
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BMCBI
2007
109views more  BMCBI 2007»
15 years 26 days ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
118
Voted
BMCBI
2008
115views more  BMCBI 2008»
15 years 26 days ago
PARPST: a PARallel algorithm to find peptide sequence tags
Background: Protein identification is one of the most challenging problems in proteomics. Tandem mass spectrometry provides an important tool to handle the protein identification ...
Sara Brunetti, Elena Lodi, Elisa Mori, Maria Stell...
DAM
2010
112views more  DAM 2010»
15 years 25 days ago
New results on optimizing rooted triplets consistency
Abstract. A set of phylogenetic trees with overlapping leaf sets is consistent if it can be merged without conflicts into a supertree. In this paper, we study the polynomial-time a...
Jaroslaw Byrka, Sylvain Guillemot, Jesper Jansson
119
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BMCBI
2006
138views more  BMCBI 2006»
15 years 25 days ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...