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» On Pairing Inversion Problems
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BMCBI
2010
90views more  BMCBI 2010»
15 years 25 days ago
Local alignment of generalized k-base encoded DNA sequence
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
Nils Homer, Stanley F. Nelson, Barry Merriman
137
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BMCBI
2007
166views more  BMCBI 2007»
15 years 25 days ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2007
165views more  BMCBI 2007»
15 years 25 days ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
BMCBI
2006
122views more  BMCBI 2006»
15 years 23 days ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
IPM
2008
100views more  IPM 2008»
15 years 22 days ago
Query-level loss functions for information retrieval
Many machine learning technologies such as support vector machines, boosting, and neural networks have been applied to the ranking problem in information retrieval. However, since...
Tao Qin, Xu-Dong Zhang, Ming-Feng Tsai, De-Sheng W...