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» On Sequence Prediction for Arbitrary Measures
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BMCBI
2008
75views more  BMCBI 2008»
14 years 12 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...
BMCBI
2007
265views more  BMCBI 2007»
14 years 12 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
STOC
1993
ACM
87views Algorithms» more  STOC 1993»
15 years 3 months ago
How to use expert advice
We analyze algorithms that predict a binary value by combining the predictions of several prediction strategies, called experts. Our analysis is for worst-case situations, i.e., we...
Nicolò Cesa-Bianchi, Yoav Freund, David P. ...
BIOCOMP
2006
15 years 1 months ago
An Approach to Selecting Putative RNA Motifs Using MDL Principle
The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Mohammad Anwar, Marcel Turcotte
ISMB
1993
15 years 1 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag