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» On Structural Analysis of Large Networks
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APVIS
2001
15 years 7 months ago
Visual Mapping of Articulable Tacit Knowledge
Tacit knowledge has long been recognised, however its research has focused largely on who is more likely to have this store of knowledge, rather than taking this one step further ...
Peter Busch, Debbie Richards, Christopher N. G. Da...
SIGIR
2008
ACM
15 years 6 months ago
Improving biomedical document retrieval using domain knowledge
Research articles typically introduce new results or findings and relate them to knowledge entities of immediate relevance. However, a large body of context knowledge related to t...
Shuguang Wang, Milos Hauskrecht
BMCBI
2010
139views more  BMCBI 2010»
15 years 6 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BMCBI
2008
84views more  BMCBI 2008»
15 years 6 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....