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» On Suboptimal Alignments of Biological Sequences
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BMEI
2008
IEEE
15 years 6 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
RECOMB
2002
Springer
16 years 7 hour ago
Significance Of inter-species matches when evolutionary rate varies
We develop techniques to estimate the statistical significance of gap-free alignments between two genomic DNA sequences, using human-mouse alignments as an example. The sequences ...
Jia Li, Webb Miller
PR
2011
14 years 6 months ago
A sum-over-paths extension of edit distances accounting for all sequence alignments
This paper introduces a simple Sum-over-Paths (SoP) formulation of string edit distances accounting for all possible alignments between two sequences, and extends related previous...
Silvia García-Díez, François ...
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BIOCOMP
2008
15 years 1 months ago
Bioinformatics Tools: Searching for Markers in DNA/RNA Sequences
Research in bioinformatics and computational biology relies heavily on algorithms that facilitate the understanding of biological processes through the application of statistical ...
Kuha Mahalingam, Omar Bagasra
BMCBI
2005
132views more  BMCBI 2005»
14 years 11 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer