314 search results - page 21 / 63 » On Suboptimal Alignments of Biological Sequences |
RECOMB
2010
Springer
15 years 6 months ago
2010
Springer
We introduce the first polynomial-time phylogenetic reconstruction algorithm under a model of sequence evolution allowing insertions and deletions—or indels. Given appropriate ...
KELSI
2004
Springer
15 years 5 months ago
2004
Springer
Multiple sequence alignment (MSA) is a vital problem in biology. Optimal alignment of multiple sequences becomes impractical even for a modest number of sequences [1] since the gen...
103
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BMCBI
2004
14 years 11 months ago
2004
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
107
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RECOMB
2003
Springer
16 years 1 days ago
2003
Springer
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
RECOMB
2006
Springer
16 years 1 days ago
2006
Springer
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...