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» On Suboptimal Alignments of Biological Sequences
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BIBM
2007
IEEE
132views Bioinformatics» more  BIBM 2007»
15 years 6 months ago
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference
In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be fu...
Feng Yue, Jijun Tang
95
Voted
BMCBI
2010
150views more  BMCBI 2010»
14 years 12 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
15 years 3 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
RECOMB
1998
Springer
15 years 4 months ago
A polyhedral approach to RNA sequence structure alignment
Ribonucleic acid (RNA) is a polymer composed of four bases denoted A, C, G, and U. It is a generally single-stranded molecule where the bases form hydrogen bonds within the same m...
Hans-Peter Lenhof, Knut Reinert, Martin Vingron
92
Voted
GECCO
2005
Springer
112views Optimization» more  GECCO 2005»
15 years 5 months ago
A multiple objective evolutionary algorithm for multiple sequence alignment
The problem of multiple sequence alignment is important for bioinformatics. This problem is widely studied and a popular tool to solve this problem is Clustal X. This work introdu...
Pasut Seeluangsawat, Prabhas Chongstitvatana