314 search results - page 33 / 63 » On Suboptimal Alignments of Biological Sequences |
RECOMB
2005
Springer
16 years 2 days ago
2005
Springer
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
TCBB
2008
14 years 11 months ago
2008
Abstract-- The trans-genomic query (TGQ) problem -- enabling the free query of biological information, even across genomes -- is a central challenge facing bioinformatics. Solution...
BMCBI
2007
14 years 12 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
SIGMOD
2004
ACM
15 years 12 months ago
2004
ACM
Growing interest in genomic research has resulted in the creation of huge biological sequence databases. In this paper, we present a hash-based pier model for efficient homology s...
NIPS
2004
15 years 1 months ago
2004
Amino acid profiles, which capture position-specific mutation probabilities, are a richer encoding of biological sequences than the individual sequences themselves. However, profi...