Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
A protein is a sequence of amino-acids of length typically less than 1, 000, where there are 20 kinds of amino-acids. In nature, each protein is folded into a well-defined three-d...
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
A recent idea for determining the three-dimensional structure of a protein uses antibody recognition of surface structure and random peptide libraries to map antibody epitope comb...