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» On Suboptimal Alignments of Biological Sequences
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AB
2007
Springer
15 years 6 months ago
Manifestation and Exploitation of Invariants in Bioinformatics
Whenever a programmer writes a loop, or a mathematician does a proof by induction, an invariant is involved. The discovery and understanding of invariants often underlies problem s...
Limsoon Wong
BMCBI
2004
105views more  BMCBI 2004»
14 years 11 months ago
eL-DASionator: an LDAS upload file generator
Background: The Distributed Annotation System (DAS) allows merging of DNA sequence annotations from multiple sources and provides a single annotation view. A straightforward way t...
Vincent Nègre, Christoph Grunau
BMCBI
2008
178views more  BMCBI 2008»
14 years 12 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
14 years 10 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
BMCBI
2008
154views more  BMCBI 2008»
14 years 12 months ago
GenomeMatcher: A graphical user interface for DNA sequence comparison
Background: The number of available genome sequences is increasing, and easy-to-use software that enables efficient comparative analysis is needed. Results: We developed GenomeMat...
Yoshiyuki Ohtsubo, Wakako Ikeda-Ohtsubo, Yuji Naga...