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» On Suboptimal Alignments of Biological Sequences
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DILS
2006
Springer
15 years 3 months ago
An Extensible Light-Weight XML-Based Monitoring System for Sequence Databases
Life science researchers want biological information in their interest to become available to them as soon as possible. A monitoring system is a solution that relieves biologists f...
Dieter Van de Craen, Frank Neven, Kerstin Koch
ICASSP
2007
IEEE
15 years 6 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
BMCBI
2005
103views more  BMCBI 2005»
14 years 11 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2007
105views more  BMCBI 2007»
14 years 11 months ago
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
Irini A. Doytchinova, Darren R. Flower
BMCBI
2011
14 years 3 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...