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» On Suboptimal Alignments of Biological Sequences
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JDA
2008
87views more  JDA 2008»
14 years 11 months ago
Lossless filter for multiple repetitions with Hamming distance
Similarity search in texts, notably in biological sequences, has received substantial attention in the last few years. Numerous filtration and indexing techniques have been create...
Pierre Peterlongo, Nadia Pisanti, Fréd&eacu...
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
14 years 11 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
BMCBI
2007
107views more  BMCBI 2007»
14 years 11 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
CSB
2003
IEEE
15 years 5 months ago
LOGOS: a modular Bayesian model for de novo motif detection
The complexity of the global organization and internal structures of motifs in higher eukaryotic organisms raises significant challenges for motif detection techniques. To achiev...
Eric P. Xing, Wei Wu, Michael I. Jordan, Richard M...
METMBS
2004
140views Mathematics» more  METMBS 2004»
15 years 1 months ago
New Techniques for Generation and Analysis of Evolutionary Trees
We introduce new distance measures for the construction and analysis of phylogenies, focusing on thioredoxin-fold proteins. Our distance measures for tree construction are based o...
Chang Wang, Stephen D. Scott, Qingping Tao, Dmitri...