314 search results - page 56 / 63 » On Suboptimal Alignments of Biological Sequences |
128
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RECOMB
2004
Springer
16 years 4 days ago
2004
Springer
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
BMCBI
2006
14 years 12 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
BMCBI
2005
14 years 11 months ago
2005
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
125
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BMCBI
2011
14 years 6 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
101
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BMCBI
2006
14 years 12 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...