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» On Suboptimal Alignments of Biological Sequences
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TCBB
2008
120views more  TCBB 2008»
14 years 11 months ago
Learning Scoring Schemes for Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of scoring scheme is critical. Even small changes in gap penalties, for example, can yield radically different alignments. A rigorous...
Eagu Kim, John D. Kececioglu
BIOCOMP
2006
15 years 1 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh
RECOMB
2009
Springer
16 years 7 days ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
98
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ECCB
2008
IEEE
15 years 6 months ago
Segment-based multiple sequence alignment
Tobias Rausch, Anne-Katrin Emde, David Weese, Andr...
ISMB
2000
15 years 1 months ago
UTR Reconstruction and Analysis Using Genomically Aligned EST Sequences
Zhengyan Kan, Warren Gish, Eric C. Rouchka, Jarret...