Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Geometric shortest paths are a major topic in computational geometry; see the survey paper by Mitchell [12]. A shortest path between two points in a simple polygon can be found in...
The study of networked systems is an emerging field, impacting almost every area of engineering and science, including the important domains of communication systems, biology, soc...
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...