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BMCBI
2006
113views more  BMCBI 2006»
14 years 10 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
COMGEO
2006
ACM
14 years 10 months ago
Computing homotopic shortest paths efficiently
Geometric shortest paths are a major topic in computational geometry; see the survey paper by Mitchell [12]. A shortest path between two points in a simple polygon can be found in...
Alon Efrat, Stephen G. Kobourov, Anna Lubiw
CORR
2006
Springer
119views Education» more  CORR 2006»
14 years 10 months ago
Network Inference from Co-Occurrences
The study of networked systems is an emerging field, impacting almost every area of engineering and science, including the important domains of communication systems, biology, soc...
Michael Rabbat, Mário A. T. Figueiredo, Rob...
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BMCBI
2007
113views more  BMCBI 2007»
14 years 10 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2007
59views more  BMCBI 2007»
14 years 10 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis
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