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BMCBI
2008
87views more  BMCBI 2008»
14 years 11 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2007
95views more  BMCBI 2007»
14 years 11 months ago
ZPS: visualization of recent adaptive evolution of proteins
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
81
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BMCBI
2008
160views more  BMCBI 2008»
14 years 11 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2008
103views more  BMCBI 2008»
14 years 11 months ago
Discovering multi-level structures in bio-molecular data through the Bernstein inequality
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Alberto Bertoni, Giorgio Valentini
113
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AMC
2006
104views more  AMC 2006»
14 years 11 months ago
Three counterexamples refuting Kieu's plan for "quantum adiabatic hypercomputation"; and some uncomputable quantum mechanical ta
-- Tien D. Kieu, in 10 papers posted to the quant-ph section of the xxx.lanl.gov preprint archive [some of which were also published in printed journals such as Proc. Royal Soc. A ...
Warren D. Smith