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» On numbers of Davenport-Schinzel sequences
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BMCBI
2010
123views more  BMCBI 2010»
15 years 1 months ago
Decoding HMMs using the k best paths: algorithms and applications
Background: Traditional algorithms for hidden Markov model decoding seek to maximize either the probability of a state path or the number of positions of a sequence assigned to th...
Daniel G. Brown 0001, Daniil Golod
BMCBI
2007
134views more  BMCBI 2007»
15 years 1 months ago
PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Ji He, Xinbin Dai, Xuechun Zhao
BMCBI
2006
158views more  BMCBI 2006»
15 years 1 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
BMCBI
2005
107views more  BMCBI 2005»
15 years 1 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
ICCS
2004
Springer
15 years 6 months ago
Evolutionary Perspectives on Protein Thermodynamics
While modern evolutionary theory has emphasized the role of neutral evolution, protein biochemistry and biophysics has interpreted the properties of proteins as largely resulting f...
Richard A. Goldstein