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» On numbers of Davenport-Schinzel sequences
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DAC
2008
ACM
16 years 2 months ago
Broadcast electrode-addressing for pin-constrained multi-functional digital microfluidic biochips
Recent advances in digital microfluidics have enabled lab-on-a-chip devices for DNA sequencing, immunoassays, clinical chemistry, and protein crystallization. Basic operations suc...
Tao Xu, Krishnendu Chakrabarty
STOC
2010
ACM
176views Algorithms» more  STOC 2010»
15 years 6 months ago
Complexity Theory for Operators in Analysis
We propose a new framework for discussing computational complexity of problems involving uncountably many objects, such as real numbers, sets and functions, that can be represente...
Akitoshi Kawamura and Stephen Cook
RECOMB
2010
Springer
15 years 3 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2007
109views more  BMCBI 2007»
15 years 2 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2007
147views more  BMCBI 2007»
15 years 1 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...