6517 search results - page 1227 / 1304 » On optimal service selection |
118
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BMCBI
2006
14 years 12 months ago
2006
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
BMCBI
2006
14 years 12 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
111
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BMCBI
2007
14 years 12 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
JACM
2006
14 years 12 months ago
2006
Abstract. Maximum likelihood (ML) is an increasingly popular optimality criterion for selecting evolutionary trees [Felsenstein 1981]. Finding optimal ML trees appears to be a very...
JCB
2006
14 years 12 months ago
2006
Maximum likelihood (ML) is increasingly used as an optimality criterion for selecting evolutionary trees, but finding the global optimum is a hard computational task. Because no g...