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» On the Accuracy and Running Time of GSAT
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BMCBI
2010
143views more  BMCBI 2010»
14 years 11 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2008
118views more  BMCBI 2008»
14 years 11 months ago
DOVIS: an implementation for high-throughput virtual screening using AutoDock
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
BMCBI
2006
95views more  BMCBI 2006»
14 years 11 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
93
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COMPUTING
2007
101views more  COMPUTING 2007»
14 years 11 months ago
Reverse engineering with subdivision surfaces
Reverse engineering is concerned with the reconstruction of surfaces from three-dimensional point clouds originating from laser-scanned objects. We present an adaptive surface rec...
P. Keller, Martin Bertram, Hans Hagen
113
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TCBB
2008
115views more  TCBB 2008»
14 years 11 months ago
Highly Scalable Genotype Phasing by Entropy Minimization
A Single Nucleotide Polymorphism (SNP) is a position in the genome at which two or more of the possible four nucleotides occur in a large percentage of the population. SNPs accoun...
Alexander Gusev, Ion I. Mandoiu, Bogdan Pasaniuc