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» On the Associative Nijenhuis Relation
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99
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BMCBI
2010
95views more  BMCBI 2010»
15 years 24 days ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
98
Voted
BMCBI
2007
137views more  BMCBI 2007»
15 years 24 days ago
GEVALT: An integrated software tool for genotype analysis
Background: Genotype information generated by individual and international efforts carries the promise of revolutionizing disease studies and the association of phenotypes with al...
Ofir Davidovich, Gad Kimmel, Ron Shamir
111
Voted
BMCBI
2010
146views more  BMCBI 2010»
15 years 24 days ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
100
Voted
BMCBI
2007
95views more  BMCBI 2007»
15 years 24 days ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
110
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 24 days ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...