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» On the Brittleness of Evolutionary Algorithms
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BMCBI
2004
133views more  BMCBI 2004»
14 years 9 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
EAAI
2010
119views more  EAAI 2010»
14 years 8 months ago
A heuristic-based framework to solve a complex aircraft sizing problem
Aircraft sizing studies consist in determining the main characteristics of an aircraft starting from a set of requirements. These studies can be summarized as global constrained o...
Céline Badufle, Christophe Blondel, Thierry...
FPL
2010
Springer
188views Hardware» more  FPL 2010»
14 years 8 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
ISDA
2010
IEEE
14 years 8 months ago
Avoiding simplification strategies by introducing multi-objectiveness in real world problems
Abstract--In business analysis, models are sometimes oversimplified. We pragmatically approach many problems with a single financial objective and include monetary values for non-m...
Charlotte J. C. Rietveld, Gijs P. Hendrix, Frank T...