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BMCBI
2008
105views more  BMCBI 2008»
14 years 12 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2008
214views more  BMCBI 2008»
14 years 12 months ago
Accelerating String Set Matching in FPGA Hardware for Bioinformatics Research
Background: This paper describes techniques for accelerating the performance of the string set matching problem with particular emphasis on applications in computational proteomic...
Yoginder S. Dandass, Shane C. Burgess, Mark Lawren...
BMCBI
2007
157views more  BMCBI 2007»
14 years 12 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
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BMCBI
2008
105views more  BMCBI 2008»
14 years 12 months ago
A gene pattern mining algorithm using interchangeable gene sets for prokaryotes
Background: Mining gene patterns that are common to multiple genomes is an important biological problem, which can lead us to novel biological insights. When family classification...
Meng Hu, Kwangmin Choi, Wei Su, Sun Kim, Jiong Yan...
BMCBI
2008
142views more  BMCBI 2008»
14 years 12 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...