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» On the Complexity of uSPR Distance
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BMCBI
2005
100views more  BMCBI 2005»
15 years 21 days ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich
119
Voted
RECOMB
2005
Springer
16 years 1 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz
113
Voted
BMCBI
2006
111views more  BMCBI 2006»
15 years 26 days ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover
123
Voted
COMPGEOM
2009
ACM
15 years 7 months ago
Coresets for polytope distance
Following recent work of Clarkson, we translate the coreset framework to the problems of finding the point closest to the origin inside a polytope, finding the shortest distance...
Bernd Gärtner, Martin Jaggi
97
Voted
CIBCB
2007
IEEE
15 years 7 months ago
An Experimental Evaluation of Inversion-and Transposition-Based Genomic Distances through Simulations
— Rearrangements of genes and other syntenic blocks have become a topic of intensive study by phylogenists, comparative genomicists, and computational biologists: they are a feat...
Moulik Kothari, Bernard M. E. Moret