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» On the Computational Power of Biochemistry
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CSREAESA
2003
15 years 2 months ago
Common Mistakes in Adiabatic Logic Design and How to Avoid Them
Most so-called “adiabatic” digital logic circuit families reported in the low-power design literature are actually not truly adiabatic, in that they do not satisfy the general...
Michael P. Frank
ISMB
1998
15 years 2 months ago
Advanced Query Mechanisms for Biological Databases
Existing query interfaces for biological databases are either based on fixed forms or textual query languages. Users of a fixed form-based query interface are limited to performin...
I-Min A. Chen, Anthony Kosky, Victor M. Markowitz,...
ISMB
1996
15 years 2 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
ISMB
1993
15 years 2 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
USENIX
1994
15 years 2 months ago
Splicing UNIX into a Genome Mapping Laboratory
The Whitehead Institute/MIT Center for Genome Research is responsible for a number of large genome mapping efforts, the scale of which create problems of data and workflow managem...
Lincoln Stein, Andre Marquis, Robert Dredge, Mary ...
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