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» On the Evolution of Evolutionary Algorithms
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BMCBI
2006
166views more  BMCBI 2006»
15 years 5 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
BMCBI
2006
130views more  BMCBI 2006»
15 years 5 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
157
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BMCBI
2007
106views more  BMCBI 2007»
15 years 5 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
148
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IJVR
2006
142views more  IJVR 2006»
15 years 5 months ago
Garden Alive: an Emotionally Intelligent Interactive Garden
In this paper, we introduce the "Garden Alive" system that allows users to interact with an emotionally intelligent virtual garden by manipulating tangible user interface...
Taejin Ha, Woontack Woo
BMCBI
2005
94views more  BMCBI 2005»
15 years 4 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya