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» On the Evolution of Evolutionary Algorithms
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WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
15 years 4 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
96
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GECCO
2010
Springer
211views Optimization» more  GECCO 2010»
14 years 11 months ago
Investigating EA solutions for approximate KKT conditions in smooth problems
Evolutionary algorithms (EAs) are increasingly being applied to solve real-parameter optimization problems due to their flexibility in handling complexities such as non-convexity,...
Rupesh Tulshyan, Ramnik Arora, Kalyanmoy Deb, Joyd...
BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
Detecting lateral gene transfers by statistical reconciliation of phylogenetic forests
Background: To understand the evolutionary role of Lateral Gene Transfer (LGT), accurate methods are needed to identify transferred genes and infer their timing of acquisition. Ph...
Sophie S. Abby, Eric Tannier, Manolo Gouy, Vincent...
BMCBI
2008
108views more  BMCBI 2008»
14 years 10 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...
BMCBI
2005
90views more  BMCBI 2005»
14 years 10 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead