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» On the Multiple Gene Duplication Problem
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100
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BMCBI
2006
82views more  BMCBI 2006»
15 years 1 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
ICASSP
2009
IEEE
15 years 8 months ago
Robust cross-race gene expression analysis
This paper develops a Bayesian network (BN) predictor to profile cross-race gene expression data. Cross-race studies face more data variability than single-lab studies. Our desig...
Hsun-Hsien Chang, Marco Ramoni
82
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BIOINFORMATICS
2007
66views more  BIOINFORMATICS 2007»
15 years 2 months ago
Gene expression network analysis and applications to immunology
We address the problem of using expression data and prior biological knowledge to identify differentially expressed pathways or groups of genes. Following an idea of Ideker et al...
Serban Nacu, Rebecca Critchley-Thorne, Peter Lee, ...
112
Voted
BMCBI
2004
113views more  BMCBI 2004»
15 years 1 months ago
Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide array
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
107
Voted
BMCBI
2010
85views more  BMCBI 2010»
15 years 1 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...