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» On the Multiple Gene Duplication Problem
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BMCBI
2010
139views more  BMCBI 2010»
14 years 11 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
BMCBI
2008
141views more  BMCBI 2008»
14 years 11 months ago
EzArray: A web-based highly automated Affymetrix expression array data management and analysis system
Background: Though microarray experiments are very popular in life science research, managing and analyzing microarray data are still challenging tasks for many biologists. Most m...
Yuerong Zhu, Yuelin Zhu, Wei Xu
BMCBI
2006
116views more  BMCBI 2006»
14 years 11 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
BMCBI
2005
162views more  BMCBI 2005»
14 years 11 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...