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BMCBI
2006
203views more  BMCBI 2006»
14 years 11 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
BMCBI
2006
98views more  BMCBI 2006»
14 years 11 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg
BMCBI
2006
115views more  BMCBI 2006»
14 years 11 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
BMCBI
2006
116views more  BMCBI 2006»
14 years 11 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2006
94views more  BMCBI 2006»
14 years 11 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...