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» On the Structure of Valiant's Complexity Classes
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BMCBI
2006
194views more  BMCBI 2006»
13 years 6 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
BMCBI
2005
105views more  BMCBI 2005»
13 years 6 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
CORR
2011
Springer
219views Education» more  CORR 2011»
13 years 1 months ago
Active Markov Information-Theoretic Path Planning for Robotic Environmental Sensing
Recent research in multi-robot exploration and mapping has focused on sampling environmental fields, which are typically modeled using the Gaussian process (GP). Existing informa...
Kian Hsiang Low, John M. Dolan, Pradeep K. Khosla
BMCBI
2010
167views more  BMCBI 2010»
13 years 6 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...