Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
A global sensitivity analysis with regional properties is introduced. This method is demonstrated on two synthetic and one hydraulic example. It can be shown that an uncertainty a...
Florian Pappenberger, Ion Iorgulescu, Keith J. Bev...
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
In many real-life situations, we know the probability distribution of two random variables x1 and x2, but we have no information about the correlation between x1 and x2; what are ...
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...