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BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
ENVSOFT
2006
125views more  ENVSOFT 2006»
14 years 9 months ago
Sensitivity analysis based on regional splits and regression trees (SARS-RT)
A global sensitivity analysis with regional properties is introduced. This method is demonstrated on two synthetic and one hydraulic example. It can be shown that an uncertainty a...
Florian Pappenberger, Ion Iorgulescu, Keith J. Bev...
BMCBI
2007
119views more  BMCBI 2007»
14 years 9 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
IJAR
2006
125views more  IJAR 2006»
14 years 9 months ago
Computing best-possible bounds for the distribution of a sum of several variables is NP-hard
In many real-life situations, we know the probability distribution of two random variables x1 and x2, but we have no information about the correlation between x1 and x2; what are ...
Vladik Kreinovich, Scott Ferson
BMCBI
2005
114views more  BMCBI 2005»
14 years 9 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...