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» On the complexity of computing determinants
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119
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BMCBI
2010
153views more  BMCBI 2010»
15 years 20 days ago
VITCOMIC: visualization tool for taxonomic compositions of microbial communities based on 16S rRNA gene sequences
Background: Understanding the community structure of microbes is typically accomplished by sequencing 16S ribosomal RNA (16S rRNA) genes. These community data can be represented b...
Hiroshi Mori, Fumito Maruyama, Ken Kurokawa
125
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 20 days ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
103
Voted
BMCBI
2010
132views more  BMCBI 2010»
15 years 20 days ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
120
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 20 days ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
87
Voted
BMCBI
2010
96views more  BMCBI 2010»
15 years 20 days ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
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