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BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2007
181views more  BMCBI 2007»
14 years 9 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan
BMCBI
2010
123views more  BMCBI 2010»
14 years 9 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
BMCBI
2010
142views more  BMCBI 2010»
14 years 9 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BMCBI
2007
163views more  BMCBI 2007»
14 years 9 months ago
Strainer: software for analysis of population variation in community genomic datasets
Background: Metagenomic analyses of microbial communities that are comprehensive enough to provide multiple samples of most loci in the genomes of the dominant organism types will...
John M. Eppley, Gene W. Tyson, Wayne M. Getz, Jill...
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